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Vicodin may also be used for purposes other than those listed in this medication if you are allergic to acetaminophen or hydrocodone, or other medicines that can make you sleepy or slow your breathing. Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone. It is similar to codeine. The combination of acetaminophen and hydrocodone is used to relieve moderate to severe pain. What is the most important information I should know about Vicodin? Do not take Vicodin with alcohol, other narcotic pain relievers such as fentanyl (Actiq, Duragesic), hydromorphone (Dilaudid, Palladone), methadone (Methadose, Dolophine), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (Oxycontin), and oxymorphone (Opana). Before using Vicodin, tell your doctor if you have. Manufacturers of Vicodin (generic or otherwise) include Abbott Laboratories (mfg. non-generic), Amerisource Health Services Corp, Cardinal Health, Drx Pharmaceutical Consultants Inc, Eckerd Corp, Hospira Inc, Knoll Laboratories Div Knoll Pharmaceutical Co, Mallinckrodt Pharm. Quality Care, Pdrx Pharmaceuticals Inc, Physicians Total Care Inc, Rx Pak Div of Mckesson Corp, Sandhills Packaging Inc and Watson Labs. Generic Vicodin by some of the aforementioned manufacturers is often substituted by pharmacies for prescriptions for Genuin.Vicodin from Abbott Labs. The generic prescriptions are much more affordable for consumers. Aggregated, Vicodin production reportedly approaches tons annually. In the United States, Vicodin production is regulated in part by the federal government which is also responsible (along with the Department of Justice and state governments) for the conviction and sentencing of anyone who breaks drug laws.